Leptosphaeria maculans

Leptosphaeria maculans
Scientific classification
Kingdom: Fungi
Division: Ascomycota
Class: Dothideomycetes
Order: Pleosporales
Family: Leptosphaeriaceae
Genus: Leptosphaeria
Species: L. maculans
Binomial name
Leptosphaeria maculans
(Sowerby) P.Karst. (1863)
Synonyms[1]

Phyllosticta brassicae
Sphaeria maculans Sowerby (1803)

Leptosphaeria maculans (anamorph Phoma lingam) is a fungal pathogen that is the causal agent of blackleg disease on Brassica crops. The major yield loss is due to stem canker.

L. maculans metabolizes brassinin, an important phytoalexin produced by Brassica species, into indole-3-carboxaldehyde and indole-3-carboxylic acid. Virulent isolates proceed through the (3-indolylmethyl)dithiocarbamate S-oxide intermediate,[2] while avirulent isolates first convert brassinin to N-acetyl-3-indolylmethylamine and 3-indolylmethylamine.[3]

As a bioengineering innovation, recently it was shown that a light-driven protein from L. maculans could be used to mediate, alongside earlier reagents, multi-color silencing of neurons in the mammalian nervous system.[4]

References

  1. ^ "Leptosphaeria maculans (Sowerby) P. Karst. 1863". MycoBank. International Mycological Association. http://www.mycobank.org/MycoTaxo.aspx?Link=T&Rec=229990. Retrieved 2011-07-05. 
  2. ^ J. Org. Chem. 1991,56, 2619-2621
  3. ^ J. Nat. Prod., 1993, 56 (5), 731–738
  4. ^ Chow, B. Y., Han, X., Dobry, A. S., et al. (January 2010). "High-performance genetically targetable optical neural silencing by light-driven proton pumps". Nature 463 (7277): 98–102. doi:10.1038/nature08652. PMC 2939492. PMID 20054397. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2939492. 

External links